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And babe I’m fist-fighting with fire Just to get close to you Can we burn something babe And I run for miles just to get a taste Must be love on the brain That’s got me feeling this way It beats me black and blue but it fucks me so good And I can’t get enough Must be love on the brain

~Rihanna, Love on the Brain

A Heart Garland

We all know that love makes us feel and act pretty nutty; but over the past few decades, researchers have studied the brains of those hit by cupid's arrow and they have come up with some pretty amazing conclusions explaining the powerful effect LOVE has on brain chemistry.


Neurotransmitters are the brain chemicals that communicate information throughout our brain and body. The holy trinity of feel-goods in LOVE chemistry is dopamine, serotonin and norepinephrine, which, when working together properly, make you feel like everything is F'ING AWESOME!

Dopamine helps control the brain's reward and pleasure centers. Dopamine also helps regulate movement and emotional responses, and it enables us not only to see rewards, but to take action to move toward them.

Serotonin is a natural mood regulator that makes you feel emotionally stable, less anxious, more tranquil, more focused and energetic. It has a deep effect on mood and social behavior, appetite and digestion, sleep, memory, sexual desire and function.

Norepinephrine is also called noradrenaline. We all know what an adrenaline drop feels like...BAM! The primary role of norepinephrine is arousal. When you're stressed, you become more awake and focused (kind of like when we get totally pissed and end up cleaning the house like a mad man). A low level of norepinephrine can leave you feeling tired and brain-foggy with little interest in life.

How does LOVE affect us physically?

Just as an SSRI (selective serotonin reuptake inhibitor) is used for depression, LOVE inhibits the uptake of the three neurotransmitters; dopamine, norepinephrine and serotonin. By preventing neurons from absorbing these neurotransmitters, they hang out in the brain outside the cells instead, where they can let it all hang out and party their socks off. When they're taken up by neurons, their impact is negated - they've essentially left the building. So an increase in extracellular dopamine, norepinephrine and serotonin makes you feel good. Really good. It's a physical response that isn't that different from the body's response to cocaine. LOVE really is a drug.

Stages of LOVE on the brain, according to's Love & Sex writer, Taryn Hillin:

ATTRACTION - Say you develop a crush on your neighbor. Every time you think about this person, you feel giddy—you feel really good. What’s happening? The neurons in your brain are releasing dopamine, a feel-good hormone and neurotransmitter associated with euphoria (as well as gambling and drug addiction). And because your brain wants you to keep pursuing this feeling, like a little love-carrot, it fires off more dopamine every time you think about the crush.

EARLY COURTSHIP - Notice how whenever you really like someone you get nervous before a date? Your palms sweat, your heart races, and you can practically feel the adrenaline surging through your body? Well, that’s because it is. In the early throes of a romantic relationship, your brain sends a signal to the adrenal gland (located on top of the kidneys) to pump out the chemicals adrenaline, epinephrine, and norepinephrine, giving you a rush of excitement. Norepinephrine is especially key. Like dopamine, it makes us feel good—but it also makes us feel infatuated and obsessed. It’s our brain’s way of saying: keep going.

THE FALL - Now you’re hooked. Suddenly you want to be around this person every minute of every day. Why? Studies (particularly the work of anthropologist Helen Fisher) have shown that the same part of your brain that activates when you’re addicted to cocaine activates when you’re in love. It’s called the limbic reward system. Basically, your brain has decided that love is essential and wants more. From an evolutionary standpoint, this response developed to help us procreate, then raise offspring together. Did you know the love drive is stronger than the sex drive?

During this phase, the limbic system continues to release dopamine, which acts as a feel-good electrical current and keeps you craving the person you love. When the object of your desire is not around, you may feel like you’re in withdrawal, motivating you to see him or her again. As with any drug, however, the high has diminishing returns—which is why, after a few months, the rush can weaken and people fall out of love. Unless, of course, they’ve become attached.

ROSE COLORED GLASSES - What flaws? While falling in love, we often ignore red flags that our friends see loud and clear. That’s because—while other parts of the limbic reward system are lighting up like a Christmas tree—the amygdala decides to shut down, according to brain scans, taking our good judgment with it. The amygdala, a set of neurons located in the temporal lobe, plays a big role in how we react to stimuli. It’s key to making judgment calls, recognizing fearful situations, and can even decipher when someone is lying to us. When people are in love, however, the amygdala takes a little nap—which clouds judgment and causes the enamored to see his or her beloved through rose-colored glasses.

ATTACHMENT - You’ve bonded. As we spend time with the object of our affection, our brains start to release oxytocin, nicknamed “the love hormone.” This neuropeptide is produced in the hypothalamus and released into our brains during times of intimacy—when mothers breastfeed their babies, for example, or when we orgasm. Studies have shown that oxytocin is key to fostering trust and commitment. Unlike the quick high of dopamine, oxytocin is subtler and sticks around longer, leading to a deeper attachment.

DEEP ATTACHMENT - Over time love can, of course, develop into deep companionship. When two people have been committed to each other for years, their brains show increased activity in the ventral pallidum. This region of the brain is rich with oxytocin and vasopressin receptors—two chemicals associated with monogamy and deep attachment—which, according to work by Helen Fisher, explains why it lights up when people experience long-term attachment. It’s the same region of the brain that activates in monogamous prairie voles, who mate for life. Brain scans show that the limbic reward system remains active during deep attachment as well—meaning couples in this stage experience the rush of early courtship along with deep attachment.

And I can’t get enough Must be love on the brain

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